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BIH - Medical Genomics Core Facility

The unit’s central interest is in translating genomics-based tools into the clinics. The introduction of the Next Generation Sequencing (NGS) -based methods has led to a major breakthrough in the routine of clinical oncology.
In line with its central interest, in January 2018, the BIH - Medical Genomics Core Facility at the CVK has launched a state of the art liquid biopsy service, as one of the first service units in the EMEA. This diagnostic tool allows for controlling and monitoring of cancer treatment and can reveal treatment resistance. In order to enable the companion diagnostic testing for tumors, the so called mutational tumor burden tests, are currently implemented and validated at the facility.
 

In order to ensure the high quality of the offered services, we put effort into implementing a number of automated NGS workflows, including low input RNA and DNA sequencing (e.g. from biopsies or FFPE/fresh frozen tumors).

In cooperation with the virology of the Charité we also offer Covid-19 genome sequencing.

The team combines solid technical wet lab expertise with strong bioinformatic/computational biology skills in implementing state of the art genomics services.

The BIH - Medical Genomics Core Facility at the Campus Virchow-Klinikum (CVK) was established in May 2017 and moved to the Campus Charité Mitte (CCM) in January 2019.